AIDS Malignancy Consortium (AMC)

The Hematology/Oncology Division is a member of the AIDS Malignancy Consortium the purview of which includes clinical trials and translational research relating to HIV patients with cancer.
This is also supported by the NCI. 


Hektoen manages several grants dealing with diabetes for Leon Fogelfeld, MD, Chairman of the Division of Endocrinology at John H. Stroger, Jr. Hospital of Cook County.
The programs, funded by pharmaceutical companies, are for the treatment and evaluation of patients with diabetes. The clinical research trials are designed to evaluate treatment in subjects with Type 2 Diabetes. 
The current trials being conducted are:  
(1) Insulin therapy in hospital wards comparing two drug protocols;  
(2) Clinical trials comparing the efficacy and safety of insulin alone verses two oral diabetic drugs; and  
(3) The study of glycemic control and safety over one year in subject with Type 2 Diabetes under diet control and exercise. 

Minority-Based Community Clinical Oncology Program (SHCC MBCCOP)

John H. Stroger, Jr. Hospital is a recipient of a large grant from the National Cancer Institute to provide access to NCI-sponsored national cooperative clinical trials in cancer treatment, prevention, and control.
The grant supports an organization called the Stroger Hospital Cook County Minority-Based Community Clinical Oncology Program (SHCC MBCCOP), which is one of 16 MBCCOPs in the U.S.. The MBCCOP office is located on the 4th floor of the Administration Building. All patients seen in the cancer clinics (hematology/oncology, surgery, radiation oncology) are screened for eligibility and offered the opportunity to participate if eligible. The spectrum available trials is broad and includes all primary tumor sites. Participation in the SHCC MBCCOP activities is an important part clinical cancer care at Stroger Hospital. The SHCC MBCCOP telephone number is (312) 864-5204. 

Pre-Hospital Airway Control Trial (PACT)

Cook County Health is joining select hospitals and emergency medical service (EMS) agencies around the country to participate in a Department of Defense-funded clinical trial aimed at improving the survival rates of people who have suffered a trauma that makes breathing difficult.

The Prehospital Airway Control Trial (PACT) is a four-year, $8.8 million study to test different strategies for securing a patient’s airway at the scene of a trauma and to see if one increases survival rates.

For more information, click here.

Women Interagency HIV Study (WIHS)

Led by Mardge Cohen, MD, CORE Center, WIHS was initiated in 1993.
WIHS maintains a cohort of approximately 250 HIV-infected and 50 uninfected at-risk women in order to investigate clinical manifestations, disease progression and outcomes of HIV infection in women. It does so by: 
  • Determining the spectrum and course of clinical manifestations of HIV infection in women. 
  • Determining the pattern and rate of decline of CD4+ cells in women and the relationship of CD4+ changes to other immunologic and virologic parameters and to clinical manifestations of HIV infection. 
  • Investigating factors which may delay or accelerate HIV-induced immune dysfunction and specific manifestations of HIV associated with clinical disease. 
  • Studying factors influencing the length of survival and the quality of life of HIV+ women, with specific attention to age, race, IV drug use and non-IV drug use and drug treatment, health care utilization, MH counseling, peer support groups, family support, social service entitlements, onsite daycare, in home care, domestic violence, homelessness, HIV risk group, use and type of antiretroviral therapy, etc. 
  • Determining the rate of incident HIV sero-conversion and identifying the factors which may increase the risk of incident HIV infection among a smaller cohort of high risk women. 
Please visit the WIHS website to view and download the WIHS Dossier of key summary statistics & publications (including a searchable database), access investigator tools necessary to establish collaborations, and also link to the CRISP database.